37 CFR 1.423 (pre-AIA)
When the inventor is insane or legally incapacitated

Taken from the Ninth Edition of the MPEP, published in March 2014

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1.423 (pre-AIA)    When the inventor is insane or legally incapacitated.

[Editor Note: Not applicable to patent applications filed under 35 U.S.C. 111(a) or 363 on or after September 16, 2012*]

In case an inventor is insane or otherwise legally incapacitated, the legal representative (guardian, conservator, etc.) of such inventor may file an international application which designates the United States of America.

[*Removed and reserved with respect to patent applications filed under 35 U.S.C. 111(a) or 363 on or after Sept. 16, 2012, 77 FR 48776, Aug. 14, 2012, effective Sept. 16, 2012]